Liteko tsa Mali li kanna tsa thusa ho lemoha mofets'e oa matsoele, ho re thuto ea haufinyane

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Kankere ea matsoele ke mofuta o tloaelehileng haholo oa mofets'e o seng oa letlalo. Ho thoe ke o mong oa mefuta e atileng haholo ea mofetše e ammeng batho, haholo lilemong tse leshome tse fetileng. India feela, ho tlalehoa mafu a fetang a milione e le 'ngoe ea mofetše oa matsoele.

Ho latela tlaleho ea morao-rao, ho lebelletsoe hore ho fumanoe litlhahlobo tse ncha ho basali, mme basali ba ka bang 40,610 ba kanna ba shoa ke lefu lena. Kankere ea matsoele ha e ame basali feela, kaha e ka ama le banna. Batho ba fetang 9,500 ba batla tlhokomelo ea mofets'e selemo le selemo mme batho ba ka bang 1,500 ba etsoa opereishene ea mofets'e selemo le selemo ^[1] .

Kankere ea matsoele e hlaha ha lisele tsa matsoele li qala ho hola ka mokhoa o sa tloaelehang, tse ikatisang ka potlako ho feta lisele tse phetseng hantle 'me li tsoele pele ho ngatafala, ho fellang ka nts'etsopele ea boima kapa hlama ^[pedi] . Ka tloaelo, mofets'e oa matsoele o fumanoe ha letšoao kapa letšoao le hlaha 'me le hlahlojoa ka thuso ea liteko le lits'ebetso tse joalo ka tlhatlhobo ea matsoele, mammogram , ultrasound ea matsoele joalo-joalo.

Leha ho le joalo, phuputso ea haufinyane e boletse hore tlhahlobo e ncha ea mali e ka thusa ho sibolla kankere ea matsoele kapele.

Teko ea Mali e ka Thusa ho Khetholla Kankere ea Matsoele Lilemo tse 5 Pele ho Matšoao a Ponahalo

E 'ngoe ea likotsi le mathata a maholo ha ho tluoa ke mofetše ke ho lemoha kamora nako. Hang ha boemo bo nametse libakeng tse ling, sekhahla sa pholoho se tlase haholo ka menyetla ea ho ipheta ^[3] .

Leha ho le joalo, ho lemoha kapele le kalafo e sebetsang ho ka thusa ho ntlafatsa sekhahla sa lefu. Empa tabeng ea mofets'e oa matsoele, tlhahlobo ea tlhaho ea tlhaho e na le moeli kaha ha e hlahise matšoao a totobetseng qalong, e ka lebisang tlhokomelong ea morao e ka amang katleho ea kalafo.

Phuputsong ea haufinyane e entsoeng ke bafuputsi ba tsoang Univesithing ea Nottingham e UK ba tiisa hore tlhahlobo ea mali e hlahlobang ho ba teng ha lithibela-mafu tse itseng e ka thusa ho lemoha mofetše oa matsoele kapele le ha bonolo ^[4] .

Teko e ka fumana li-Autoantibodies

Bafuputsi ba ile ba tsoela pele ho hlalosa mokhoa oa tlhahlobo ea mali ka ho hlalosa hore ha mofetše o le teng, 'mele oa hau o hlahisa li-antigen tse bakang karabelo ea' mele ea ho itšireletsa mafung. Hona, ho etsa hore sesole sa 'mele se itšoare ka lintho tseo ka ho lokolla li-autoantibodies, tse tla fumanoa ka tlhahlobo ea mali le ho bontša hore na kankere ea matsoele e teng kapa che.

Qalong, bafuputsi ba ile ba hlahisa li-antigen tse amanang le hlahala (TAAs) tse ikhethileng bakeng sa mofets'e oa matsoele o thusitseng ho utloisisa boteng ba li-autoantigen maling tse amanang le karabelo ea li-TAAs tse ikhethileng tsa mofets'e. ^[5] .

E mong oa bafuputsi Daniyah Alfattani o itse, 'Liphetho tsa boithuto ba rona li bontšitse hore mofets'e oa matsoele o hlohlelletsa li-autoantibodies khahlano le likarolo tsa li-antigen tse amanang le hlahala. Re atlehile ho lemoha mofets'e ka nepo e nepahetseng ka ho khetholla li-autoantibodies tse maling ', hape re hatelletse tlhokeho ea ho nts'etsapele le ho netefatsa tlhahlobo ea mali ^[6] .

Boithuto bo bontša litholoana tse tšepisang

Bafuputsi ba thabile haholo ka sephetho sa boithuto hobane liphetho lia khothatsa ebile li bonts'a hore ho a khonahala ho fumana letšoao la mofets'e oa pele oa matsoele. 'Hang ha re se re ntlafalitse ho nepahala ha teko, e ntan'o bula monyetla oa ho sebelisa tlhahlobo e bonolo ea mali ho ntlafatsa ho lemoha lefu lena kapele', ho boletse mofuputsi ka mokhoa o motle ^[6] .

Ka thuto e nang le batho ba fetang 90 ba arabelitsoeng, ho ka nahanoa hore liphetho li nepahetse ka nepo mme tlhahlobo e ncha ea mali e ka ba molemo ho thusa litsebi tsa bongaka le lingaka ho lemoha boteng ba mofets'e oa matsoele ho fihlela lilemo tse 5 pele matšoao a bonahalang a hlaha.

Ka Tsebiso ea ho Qetela ...

Ka boithuto bo hlahisang litholoana tse ntle, bafuputsi ba ikemiselitse ho holisa sebaka sa boithuto hobane tlhahlobo ea mali bakeng sa tlhahlobo ea mofets'e ea matsoele e tla ba litšenyehelo, hape e tla ba mokhoa o atlehang le o bonolo oa ho hlahloba ha o bapisoa le mehato e teng ^[7] . Liteko tse tšoanang li nts'etsopele bakeng sa mefuta e meng ea mofets'e, ho kenyeletsoa kankere ea matšoafo, pancreatic, colorectal le sebete.

1. [1]Lauren, S. & Cassell, M. Opereishene ea matsoele, Sepetlele sa Lenox Hill, Sepolesa sa New York City Alice, MD, motsamaisi oa setereke sa Westchester, opereishene ea matsoele, Setsi sa Kankere ea Bophelo sa Northwell, Sleepy Hollow, NY NCRI (Setsi sa Naha sa Patlisiso ea Kankere, UK), phatlalatso ea litaba, Nov. 2, 2019
2. [pedi]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Kopo ea Patent No. 15 / 564,089.
3. [3]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-Vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Kopo ea Patent No. 10 / 214,591.
4. [4]Yadav, S., Kashaninejad, N., Masud, M. K., Yamauchi, Y., Nguyen, N. T., & Shiddiky, M. J. (2019). Li-autoantibodies e le tlhahlobo ea kankere ea ho hlahloba le ho tseba esale pele: Mekhoa ea ho lemoha le mekhoa. Biosensors le Bioelectronics, 111315.
5. [5]Jiang, X. H., Yao, Z. Y., He, X., Zhang, J. B., Xie, K., Chen, J., ... & Yie, S. M. (2019). Bohlokoa ba bongaka ba mali a anti-TOPO48 autoantibody le mali a pholohang-a bonts'ang lisele tsa mofetše ho bakuli ba nang le karolo ea pele ea endometrial carcinoma. Li-Archives tsa mafu a basali le tsa pelehi, 299 (1), 229-237.
6. [6]Seluk, L., Taliansky, A., Yonath, H., Gilburd, B., Amital, H., Shoenfeld, Y., & Kivity, S. (2019). Sesepa se seholo sa li-paraneoplastic neurological autoantibodies diagnostics le litekanyetso tsa ho tseba esale pele. Kliniki ea Immunology, 199, 29-36.
7. [7]Khayeka-Wandabwa, C., Ma, X., Cao, X., Nunna, V., Pathak, J. L., Bernhardt, R., ... & Bureik, M. (2019). Lera la lera la lehae la CYP4Z1 le CYP19A1 le phumano ea li-autoantibodies tse khahlanong le CYP19A1 bathong. Machabeng immunopharmacology, 73, 64-71.

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