L-CARNITINE: MELEMO EA EONA, MEHLOLI LE LITLAMORAO

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E tlameha ho shebella

Se ke oa Lahleha

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L-carnitine ke amino acid, e hlahisoang ka tlhaho 'meleng. Sehlahisoa sa amino acid ke tlatsetso e sebelisoang hangata. Phepo e bapala karolo ea bohlokoa tlhahisong ea matla 'meleng oa hau. Ka ho tsamaisa mafura a 'mele oa hau ho mitochondria, eo le eona e thusang ho chesa mafura le ho a fetola matla.

L-carnitine e hlahisoa ka har'a mmele oa hau, e hlahisoang ke amino acid lysine le methionine. Hore 'mele oa hau o hlahise L-carnitine e hlokahalang, o tlameha ho ba le vithamine C. Ntle le moo, L-carnitine e ka fumaneha ka nyane ka ho ja lijo tse kang nama, lebese, tlhapi jj. e fumaneha hape ka mokhoa oa litlatsetso ^[1] ^[pedi] .

Amino acid ke mofuta o tloaelehileng oa `` carnitine '' o phelang ka tlhaho (lebitso le tloaelehileng bakeng sa quaternary ammonium komponeng e amehang metabolism ea liphoofolo tse anyesang, limela le libaktheria tse ling), e fumanehang hape ka sebopeho sa D-carnitine, Acetyl-L-carnitine, Propionyl-L-carnitine, le L-carnitine L-tartrate ^[3] .

Melemo ea bophelo bo botle ba L-carnitine

1. Ho fokotsa boima ba Aids

L-carnitine e ile ea tuma linakong tsa morao tjena ka bokhoni ba eona ba ho thusa ho theola boima ba 'mele. Tlatsetso ea amino acid e sebetsa ka ho tsamaisa mafura a li-acid liseleng tsa hau, tse tla chesoa hore e be matla. Le ha ho bile le likhanyetsano mabapi le bokhoni ba tlatsetso ba ho khothaletsa ho theola boima ba 'mele, phuputso e entsoeng ho batho ba batenya ho tlola e tšehetse taba ea hore L-carnitine e thusa ho theola boima ba' mele ^[4] .

2. E ntlafatsa ts'ebetso ea boko

Boithuto bo bong bo bontšitse hore L-carnitine e ka thusa ho ntlafatsa tšebetso ea boko ba hau. Ka mantsoe a mang, e ka thusa ho thibela ho putlama hoa kelello ho amanang le lilemo, ho thusa ho ntlafatsa bokhoni ba motho ba ho ithuta, le ho thusa ho etsolla phokotseho ea ts'ebetso ea boko ho thibela ho qala ha mafu a Alzheimer's le a mang a boko. ^[5] .

3. Ho laola bophelo ba pelo

L-carnitine e hokahantsoe le ho fokotsa khatello ea mali le ts'ebetso ea ho ruruha e amanang le lefu la pelo. Ho boetse ho tiisitsoe hore e na le bokhoni ba ho ntlafatsa maemo a batho ba nang le mathata a tebileng a pelo, joalo ka lefu la pelo le lefu la pelo le sa foleng. ^[6] .

4. Ho matlafatsa ts'ebetso

Boithuto bo fapaneng bo bontšitse melemo, leha e le nyane, L-carnitine e na le eona ho ntlafatseng ts'ebetso ea motho ea lipapali. Ka lebaka la thepa ena, L-carnitine ke lebitso le tloaelehileng lebaleng la lipapali. E ka thusa ho ntlafatsa boikoetliso ba hau ba 'mele, ea eketsa phepelo ea oksijene mesifa ea hau, ea ntlafatsa mokoka oa hau, ea fokotsa bohloko ba mesifa le ho eketsa tlhahiso ea lisele tse khubelu tsa mali ^[3] .

5. Ho laola lefu la tsoekere

L-carnitine e ka u thusa ho laola le ho fokotsa matšoao a lefu la tsoekere, haholo-holo mofuta oa 2 oa lefu la tsoekere. Ho boetse ho molemo ho sebetsana le lisosa tsa kotsi tsa boemo bona, kaha amino acid e ka thusa ho fokotsa maemo a tsoekere maling ^[6] .

Ho boetse ho thoe e molemo bakeng sa ho fana ka phomolo ho bohloko ba sefuba, lefu la liphio, hyperthyroidism, ho hloka thari ha banna, makhopho, ho lahleheloa ke moriri, autism, ho otla ha pelo ka tsela e sa tloaelehang, methapo e koetsoeng, mokhathala, boima ba 'mele bo tlaase le tse ling tse fapaneng. Leha ho le joalo, ho na le khaello ea lithuto mabapi le ts'ebeliso le katleho ea L-carnitine maemong a fapaneng ^[7] .

Litla-morao tsa L-carnitine

L-carnitine e tlatselletsa kapa liente, leha e sireletsehile bakeng sa ts'ebeliso ea batho, e ka baka litlamorao ho batho ba itseng. Tse ling tsa litla-morao tse tloaelehileng tsa amino acid li boletsoe ka tlase ^[8] .

Ho nyekeloa
Ho hlatsa
Bohloko ba mala
Ho heletsa
Letšollo
Ho oa
Monko oa litlhapi morong, phefumoloho le mofufutso

Ntle le moo, basali ba baimana le ba anyesang ba lokela ho qoba ho ja L-carnitine ^[9] . L-carnitine e feteletseng e ka baka ho hloleha ha liphio, hape ea mpefatsa matšoao a hypothyroidism. Hape, qoba ho ja L-carnitine bakeng sa ho sebetsana le ho oela, haeba u se u kile ua oa pele.

Tekanyo ea L-carnitine

Tlhokomeliso: U tlameha ho buisana le ngaka pele u kenyelletsa li-supplement tsa L-carnitine kapa liente mekhoeng ea hau.

Tekanyo e boletsoeng mona ke ea batho ba baholo ^[10] .

Ho haella ha L-carnitine: 990 mg, makhetlo a mabeli ho isa ho a mararo ka letsatsi (matlapa kapa tharollo ea molomo).

Bohloko ba sefuba: 900 mg ho 2 g ho 1 ho 2 tekanyetso e arotsoeng letsatsi le letsatsi bakeng sa libeke tse 2 ho isa ho likhoeli tse 6.

Tekanyo e tloaelehileng ea L-carnitine ke 500-2,000 mg ka letsatsi.

Ka Tsebiso ea ho Qetela ....

Bakeng sa likokoana-hloko, ho hlahisa le ho fumana L-carnitine ho ka ba thata ka lebaka la khaello ea ts'ebeliso ea nama le tlhapi. Ho joalo le ka batho ba nang le mathata a itseng a lefutso. Leha ho le joalo, motho a ka fumana palo e hlokahalang ea L-carnitine ka ho sebelisa li-supplement tsa L-carnitine.

Sheba Litšupiso tsa Sengoloa

[1]Tšimo, R., Riede, L., Lugo, J., & Bellamine, A. (2018). l-Carnitine supplementation ea ho fola kamora ho ikoetlisa. Metsoako, 10 (3), 349.
[pedi]Koeth, R. A., Lam-Galvez, B. R., Kirsop, J., Wang, Z., Levison, B. S., Gu, X., ... & Culley, M.K (2018). l-Carnitine lijong tse omnivorous e baka mokhoa oa atherogenic gut microbial tseleng ea batho. Leqephe la Phuputso ea Bongaka, 129 (1), 373-387.
[3]Novakova, K., Kummer, O., Bouitbir, J., Stoffel, S. D., Hoerler-Koerner, U., Bodmer, M., ... & Krähenbühl, S. (2016). Phello ea tlatsetso ea l-carnitine 'meleng oa' mele oa 'mele,' mele oa mesifa ea metabolism le ts'ebetso ea 'mele ho batho ba jang limela. Koranta ea Europe ea phepo e nepahetseng, 55 (1), 207-217.
[4]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2015). Litholoana tsa antiinflammatory tsa L-carnitine supplementation (1000 mg / d) ho bakuli ba methapo ea mali. Nutrition, 31 (3), 475-479.
[5]Chan, Y. L., Saad, S., Al-Odat, I., Oliver, B. G., Pollock, C., Jones, N. M., & Chen, H. (2017). Tlatsetso ea 'L-carnitine' ea bo-mme e ntlafatsa bophelo bo botle ba bongoana ho tsoa mosing oa sakerete bo-mme ba pepesitseng.
[6]Fukami, K., Yamagishi, S. I., Sakai, K., Kaida, Y., Yokoro, M., Ueda, S., ... & Okuda, S. (2015). Tlatsetso ea molomo oa L-carnitine e eketsa trimethylamine-N-oxide empa e fokotsa matšoao a kotsi ea vascular ho bakuli ba hemodialysis. Journal of pharmacology ea methapo ea pelo, 65 (3), 289-295.
[7]da Silva, G. S., de Souza, C. W., da Silva, L., Maciel, G., Huguenin, A. B., de Carvalho, M., ... & Colafranceschi, A. (2017). Phello ea Tlatsetso ea L-Carnitine mabapi le Phetolo e Fetohileng ho bakuli ba nang le Ischemic Heart Mafu a Etsoang ke Coronary Artery Bypass Grafting: Teko e Laoloang, e Laoloang ka Sebaka. Li-Annal tsa phepo e nepahetseng le metabolism, 70 (2), 106.
[8]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2016). Liphello tsa tlatsetso ea L-carnitine ho lifaele tsa lipid ho bakuli ba nang le lefu la methapo ea methapo. Lipid ka bophelo bo botle le mafu, 15 (1), 107.
[9]Pala, R., Genc, E., Tuzcu, M., Orhan, C., Sahin, N., Er, B., ... & Sahin, K. (2018). L-Carnitine supplementation e eketsa polelo ea PPAR-γ le ba tsamaisang tsoekere ka mesifa ea masapo ea likhoto tse sa sebetseng hantle le tse matla. Biology ea lisele le limolek'hule (Noisy-le-Grand, France), 64 (1), 1-6.
[10]Imbe, A., Tanimoto, K., Inaba, Y., Sakai, S., Shishikura, K., Imbe, H., ... & Hanafusa, T. (2018). Liphello tsa tlatsetso ea L-carnitine ho boleng ba bophelo ho bakuli ba nang le lefu la tsoekere ba nang le mesifa ea mesifa. Koranta ea Endocrine, EJ17-0431.